Lamivudine Triphosphate-15N2,13C Triethylamine Salt (90%)

Chemical Name:Lamivudine Triphosphate-15N2,13C Triethylamine Salt (90%)
Synonyms:((2R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl-15N2,13C Tetrahydrogen Triphosphate Triethylammonium Salt;
Alternate CAS #:143188-53-8
Molecular Formula:C₇¹³CH₁₄N¹⁵N₂O₁₂P₃S • [ C₆H₁₅N]ₓ
Molecular Weight:472.18 + (101.19)x
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
Applications:Isotope labelled Lamivudine Triphosphate Triethylamine Salt (L172510), a metabolite of Lamivudine (L172500), a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.
References:Burgess, K., et al.: Chem. Rev., 100, 2047 (2000), Gallois-Montbrun, S., et al.: Biochem. Pharmacol., 68, 1749 (2004); Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),
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