Liberine

Chemical Name:Liberine
Synonyms:O2,1,9-Trimethyluric Acid; 7,9-Dihydro-2-methoxy-1,9-dimethyl-1H-purine-6,8-dione; 2-Methoxy-1,9-dimethyl-1H-purine-6,8(7H,9H)-dione
CAS Number:56119-16-5
Molecular Formula:C₈H₁₀N₄O₃
Molecular Weight:210.19
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Liberine is an alkaloid metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses.
References:Kappeler, A.W., Baumann, T.W.: Colloque Scientifique International sur le Cafe, 11th, 273 (1985); Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988)
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