Nα-Acetyl-L-Lysine-13C6,15N2

Chemical Name:Nα-Acetyl-L-Lysine-13C6,15N2
Synonyms:6-Amino-L-2-acetamidohexanoic Acid-13C6,15N2; N2-Acetyl-L-lysine-13C6,15N2; N2-Acetyllysine-13C6,15N2
Alternate CAS #:1946-82-3
Molecular Formula:C₂¹³C₆H₁₆¹⁵N₂O₃
Molecular Weight:196.17
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Nα-Acetyl-L-Lysine-13C6,15N2 is the labeled compound of Nα-Acetyl-L-Lysine (A185540). Nα-Acetyl-L-Lysine is an antibacterial lysine analogue that targets lysine riboswitches. Nα-Acetyl-L-Lysine is used in the metabolomic characterization of ovarian epithelial carcinomas which allows for better therapeutic management of patients. The presence of Nα-Acetyl-L-Lysine and other N-acetylated amino acids in the urine can be used to detect aminoacylase I deficiency.
References:Gerlo, E. et al.: Anal. Chim. Acta, 571, 191 (2006); Ben Sellem, D. et al.: J. Oncol., 174019, 9 (2011); Blount, K.F. et al.: Nat. Chem. Biol., 3, 44 (2007);
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