N-(3-Ethynyphenyl)-7,8-bis(2-methoxyethoxy)quinazolin-4-amine

Chemical Name:N-(3-Ethynyphenyl)-7,8-bis(2-methoxyethoxy)quinazolin-4-amine
Molecular Formula:C₂₂H₂₃N₃O₄
Molecular Weight:393.44
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-(3-Ethynyphenyl)-7,8-bis(2-methoxyethoxy)quinazolin-4-amine is a derivative compound of Erlotinib (E625008), that functions as a EGFR-targeted drug in the treatment of non-small cell lung cancer and also as a small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival.
References:Yao, T., et al.: Ther. Targets Neurol. Dis., 2, 585 (2015); Zhu, B., et al.: Xiandai Zhenduan Yu Zhiliao, 25, 4679 (2014);
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