N-Destertbutyl Finasteride

Chemical Name:N-Destertbutyl Finasteride
Synonyms:N-(1,1-dimethylethyl)-3-oxo-4-aza-5b-androst-1-ene-17b-carboxamide; 5b Finasteride; (4aR,4bS,6aS,7S,9aS,9bS,11aS)-1-(tert-butyl)-4a,6a,-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,10,11,11a-tetradecahydro-1H-indenco[5,4-f]quinoline-7-carboxamide
Molecular Formula:C₂₃H₃₆N₂O₂
Molecular Weight:372.54
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Destertbutyl Finasteride is an impurity of Finasteride(F342000) which is an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone.
References:Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993), Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997), McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998),
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