N-Hydroxy Labetalol

Chemical Name:N-Hydroxy Labetalol
Synonyms:2-Hydroxy-5-(1-hydroxy-2-(hydroxy(4-phenylbutan-2-yl)amino)ethyl)benzamide
Molecular Formula:C₁₉H₂₄N₂O₄
Molecular Weight:344.41
Category:Standards; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Hydroxy Labetalol is an impurity of (R,R)-Labetalol Hydrochloride(L096500) which is a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol Hydrochloride is also used as an antihypertensive.
References:Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989),
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