N-Hydroxy Riluzole O-β-D-Glucuronide-13C,15N2

Chemical Name:N-Hydroxy Riluzole O-β-D-Glucuronide-13C,15N2
Synonyms:1-O-[[6-(Trifluoromethoxy)-2-benzothiazolyl]amino]-β-D-glucopyranuronic Acid-13C,15N2
Alternate CAS #:Unlabelled: 1394929-56-6
Molecular Formula:C₁₃¹³CH₁₃F₃¹⁵N₂O₈S
Molecular Weight:429.3
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Hydroxy Riluzole O-β-D-Glucuronide-13C,15N2 is the isotope labelled analog of N-Hydroxy Riluzole O-β-D-Glucuronide (H953670); a metabolite of Riluzole (R510000) which is a neuroprotective agent that modulates glutamatergic transmission. Also a glutamate release inhibitor and anticonvulsant.
References:McDonnell, M.E., et al.: Bioorg. Med. Chem., 20, 5642 (2012); Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985); Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993); Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)
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