N-(Methoxycarbonyl)-3-(methyl-d3)-L-valine-4,4,4,4′,4′,4′-d6

Chemical Name:N-(Methoxycarbonyl)-3-(methyl-d3)-L-valine-4,4,4,4′,4′,4′-d6
CAS Number:1092539-97-3
Molecular Formula:C₈H₆D₉NO₄
Molecular Weight:198.26
Category:Building Blocks; Miscellaneous;
Applications:N-(Methoxycarbonyl)-3-(methyl-d3)-L-valine-4,4,4,4′,4′,4′-d6 is an intermediate used in the synthesis of Atazanavir-d9 (A790053), which is the deuterated analog of Atazanavir (A790051), a azapeptide HIV protease inhibitor derivative. Atazanavir have been investigated as potential treatment of human immunodeficiency virus (HIV) and for anticancer purposes.
References:Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004), Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004),
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