Drug Delivery

Chemical Name:Imidafenacin-d13Synonyms:2-Methyl-α,α-diphenyl-1H-imidazole-1-butanamide-d13; 4-(2-Methyl-1-imidazolyl)-2,2-diphenylbutanamide-d13; 4-(2-Methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide-d13; Imidafenacin-d13; KRP 197-d13; Uritos-d13;Alternate CAS #:Unlabelled: 170105-16-5Molecular Formula:C₂₀H₈D₁₃N₃OMolecular Weight:332.48Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Imidafenacin-d13 is deutirium labelled imidafenacin which is a novel therapeutic agent for overactive bladder with antimuscarinic activity, on mediator release from urothelium and detrusor overactivity induced by cerebral infarction.References:Andersson, K., et al.: Eur. […]

Chemical Name:Iloperidone 3,4-DehydropiperidineSynonyms:1-(4-(3-(4-(6-Fluorobenzo[d]isoxazol-3-yl)-5,6-dihydropyridin-1(2H)-yl)propoxy)-3-methoxyphenyl)ethanoneMolecular Formula:C₂₄H₂₅FN₂O₄Molecular Weight:424.46Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Iloperidone 3,4-Dehydropiperidine is an impurity of Iloperidone (I267200), a combined dopamine (D2) and serotonin (5HT2) receptor antagonist.References:Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995); Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995); Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996)To ensure […]

Chemical Name:IlepatrilSynonyms:(4S,7S,12bR)-7-[[(2S)-2-(Acetylthio)-3-methyl-1-oxobutyl]amino]-1,2,3,4,6,7,8,12b-octahydro-6-oxo-pyrido[2,1-a][2]benzazepine-4-carboxylic Acid; AVE-7688;CAS Number:473289-62-2Molecular Formula:C₂₂H₂₈N₂O₅SMolecular Weight:432.53Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A dual angiotensin-converting enzyme and neutral endopeptidase inhibitor, for the potential treatment of hypertension and diabetic nephropathy. Ilepatril is currently in phase IIb/III clinical trials for hypertension and phase II trials for diabetic nephropathy.References:Tabrizchi, R., et al.: Drugs, 63, 2185 (2003), Azizi, […]

Chemical Name:N-(6-(3-(4-(Bis(methyl-d3)amino)butoxy)-5-propoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-3,4-dimethoxybenzenesulfonamideMolecular Formula:C32H36D6N4O8SMolecular Weight:648.8Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-(6-(3-(4-(Bis(methyl-d3)amino)butoxy)-5-propoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-3,4-dimethoxybenzenesulfonamide is a useful research chemical compoundTo ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature […]

Chemical Name:4,4’-(8-Fluoropentaazaphenalene-2,5-diyl)bis((N3-methyl)triphenylamine)Synonyms:I-423;4,4′-(8-Fluoro-1,3,3a1,4,6-pentaazaphenalene-2,5-diyl)bis(N3-methyl-N1,N1-diphenylbenzene-1,3-diamine);Molecular Formula:C₄₆H₃₆FN₉Molecular Weight:733.86Category:Building Blocks; Miscellaneous;Applications:I-423 is a useful research chemical.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with […]

Chemical Name:Ibrutinib M25Synonyms:4-Amino-γ-[[(1-oxo-2-propen-1-yl)amino]methyl]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-1-butanoic AcidCAS Number:1839090-60-6Molecular Formula:C₂₅H₂₄N₆O₄Molecular Weight:472.5Category:Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors;Applications:Ibrutinib M25, is an impurity of Ibrutinib (I124970), a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.References:MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)To ensure the stability of our products, the efficient express delivery service will be used. We also […]

Chemical Name:2-Hydroxy ValbenazineSynonyms:(S)-(2R,3R,11bR)-3-(2-Hydroxypropan-2-yl)-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoateMolecular Formula:C₂₃H₃₆N₂O₅Molecular Weight:420.54Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-Hydroxy Valbenazine is an impurity of Valbenazine (V087000), a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia.References:O’Brien, C. et al.: Movement Dis., 30, 1681 (2015);To ensure the stability of our products, the efficient express delivery service will be used. […]

Chemical Name:N-Hydroxyaristolactam ISynonyms:6-Hydroxy-8-methoxybenzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-oneCAS Number:944954-53-4Molecular Formula:C₁₇H₁₁NO₅Molecular Weight:309.27Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-Hydroxyaristolactam I, is a derivative of Aristolactam I (A767420), classified as human carcinogen associated with human nephropathy and urothelial cancer.References:Stiborova, M. et al.: Toxicol. Sci., 125, 345 (2012);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the […]

Chemical Name:3-Hydroxymethylcholanthrene-2-oneSynonyms:3-(Hydroxymethyl)-benz[j]aceanthrylen-2(1H)-one (9CI)CAS Number:177327-84-3Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₄O₂Molecular Weight:298.33Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene-2-one has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee […]

Chemical Name:3-Hydroxymethylcholanthrene-1-oneSynonyms:3-(hydroxymethyl)-benz[j]aceanthrylen-1(2H)-one (9CI)CAS Number:177237-83-2Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₄O₂Molecular Weight:298.33Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene-1-one has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will be used. We […]