rac-4’-O-Desmethyl-4’-O-ethyl Apremilast

Chemical Name:rac-4’-O-Desmethyl-4’-O-ethyl Apremilast
Synonyms:N-(2-(1-(3,4-Diethoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; Apremilast Impurity D
Molecular Formula:C₂₃H₂₆N₂O₇S
Molecular Weight:474.53
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:rac-4’-O-Desmethyl-4’-O-ethyl Apremilast is an impurity of Apremilast (A729700); an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.
References:Gan, E. et al.: BioDrugs, 27, 359 (2013); Pathan, E. et al.: Annal. Rheum. DIs., 72, 1475 (2013)
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