rac-4’-O-Ethyl-3’-O-methyl Apremilast-d5

Chemical Name:rac-4’-O-Ethyl-3’-O-methyl Apremilast-d5
Synonyms:N-(2-(1-(4-Ethoxy-3-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide-d5; Apremilast Impurity E-d5
Molecular Formula:C₂₂H₁₉D₅N₂O₇S
Molecular Weight:465.53
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:rac-4’-O-Ethyl-3’-O-methyl Apremilast-d5 is the isotope labelled analog of rac-4’-O-Ethyl-3’-O-methyl Apremilast (E679595); an impurity of Apremilast (A729700) which is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.
References:Gan, E. et al.: BioDrugs, 27, 359 (2013); Pathan, E. et al.: Annal. Rheum. DIs., 72, 1475 (2013)
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