rac 7,14-Dihydroxy Efavirenz 7-O-β-D-Glucuronide

Chemical Name:rac 7,14-Dihydroxy Efavirenz 7-O-β-D-Glucuronide
Synonyms:6-Chloro-1,4-dihydro-4-[(1-hydroxycyclopropyl)ethynyl]-2-oxo-4-(trifluoromethyl)-2H-3,1-benzoxazin-7-yl β-D-Glucopyranosiduronic Acid
Alternate CAS #:4S-isomer: 252343-35-4
Molecular Formula:C₂₀H₁₇ClF₃NO₁₀
Molecular Weight:523.8
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
Applications:rac 7,14-Dihydroxy Efavirenz 7-O-β-D-Glucuronide is a metabolite of (S)-Efavirenz (E425000); a nonnucleoside HIV-1 reverse transcriptase inhibitor.
References:Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995); Mutlib, A.E., et al.: Drug Metab. Dispos., 27, 1319 (1999)
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