rel-(2R,3S)-4-Benzyl-2-(4-fluorophenyl)morpholin-3-yl 3,5-Bis(trifluoromethyl)benzoate

rel-(2R,3S)-4-Benzyl-2-(4-fluorophenyl)morpholin-3-yl 3,5-Bis(trifluoromethyl)benzoate

Chemical Name:rel-(2R,3S)-4-Benzyl-2-(4-fluorophenyl)morpholin-3-yl 3,5-Bis(trifluoromethyl)benzoate
Molecular Formula:C₂₆H₂₀F₇NO₃
Molecular Weight:527.43
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:rel-(2R,3S)-4-Benzyl-2-(4-fluorophenyl)morpholin-3-yl 3,5-Bis(trifluoromethyl)benzoate can be synthesized from N-Benzylethanolamine (B276445) which is used in the synthesis of imidazoles as potent calcitonin (CGRP) antagonists. Also it aids in the preparation of benzofused hydroxamix acids, as useful fragments for the synthesis of histone deacetylase inhibitors.
References:Tora, G. et al.: Bioorg. Med. Chem. Lett., 23, 5684 (2013); Marastoni, E. et al.: Bioorg. Med. Chem. Lett., 23, 4091 (2013);
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