tert-Butyl β-Carboline-3-carboxylate

Chemical Name:tert-Butyl β-Carboline-3-carboxylate
Synonyms:9H-Pyrido[3,4-b]indole-3-carboxylic Acid 1,1-Dimethylethyl Ester; β-CCT;
CAS Number:93835-05-3
Molecular Formula:C₁₆H₁₆N₂O₂
Molecular Weight:268.31
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:βCCt acts as an α1selective antagonist and benzodiazepine mixed agonist/antagonist. βCCt has been shown to reduce alcohol self-administration in alcohol preferring (P) and high alcohol drinking (HAD) rats.
References:Allen, M., et al.: J. Med. Chem., 33, 2343 (1990); June, H., et al.: Brain Res., 794, 103 (1998); Yin, W., et al.: Bioorg. Med. Chem., 18, 7548 (2010); Harvey, S., et al.: J. Neurosci., 22, 3765 (2002),
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