(Z)-Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate

Chemical Name:(Z)-Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate
Molecular Formula:C₁₉H₂₃ClO₆
Molecular Weight:382.84
Category:Building Blocks; Miscellaneous;
Applications:(Z)-Ethyl 4-(2-(tert-butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate is an intermediate for the synthesis of O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine (D289480), which is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.
References:Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.