α-Cyclohexyl-α-hydroxy-3-cyclohexene-1-acetic Acid 4-(Diethylamino)-2-butyn-1-yl Ester Hydrochloride

Chemical Name:α-Cyclohexyl-α-hydroxy-3-cyclohexene-1-acetic Acid 4-(Diethylamino)-2-butyn-1-yl Ester Hydrochloride
Synonyms:Oxybutynin EP Impurity A;
Molecular Formula:C₂₂H₃₅NO₃.HCl
Appearance:White to Off-White Low-Melting Solid to Solid
Melting Point:>42°C (dec.)
Molecular Weight:397.98
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:α-Cyclohexyl-α-hydroxy-3-cyclohexene-1-acetic Acid 4-(Diethylamino)-2-butyn-1-yl Ester Hydrochloride (Oxybutynin EP Impurity A) is the cyclohexyl analog of Oxybutynin (O868525), an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.
References:Giannini, I. et al.: Talanta, 80, 781 (2009); Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)
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