(1R,2S)-Darunavir

Chemical Name:(1R,2S)-Darunavir
Synonyms:(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2R,3S)-4-(4-Amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate; N-[(1R,2S)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl Ester
CAS Number:1402142-63-5
Molecular Formula:C₂₇H₃₇N₃O₇S
Molecular Weight:547.66
Category:Standards; Enzyme Activators and Inhibitors;
Applications:1R,2S)-Darunavir is a diastereomer of Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.
References:Babu, K.R., et. al.: Indian J. Chem. B, 51B, 849 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)
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