4-Despiperidinyl-4-(5-oxopentylamino) Dipyridamole

Chemical Name:4-Despiperidinyl-4-(5-oxopentylamino) Dipyridamole
Synonyms:5-[(2,6-bis[bis(2-hydroxyethyl)amino]-8-(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-4-yl)amino]pentanal
Molecular Formula:C₂₄H₄₀N₈O₅
Molecular Weight:520.62
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Despiperidinyl-4-(5-oxopentylamino) Dipyridamole is an impurity of Dipyridamole (D492625); a selective inhibitor of phosphodiesterase V (PDE 5), a potent coronary vasodilator drug, an adenosine transport inhibitor, and an inhibitor of platelet aggregation.
References:Buchalter, M.B., et al.: Postgrad. Med. J., 66, 531 (1990); Sundaram, M., et al.: J. Biol. Chem., 273, 21519 (1998); Denis, D., et al.: Eur. J. Pharmacol., 367, 343 (1999)
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