N4-Des Pyrazolo N4-Acetoacetyl Teneligliptin-d8

Chemical Name:N4-Des Pyrazolo N4-Acetoacetyl Teneligliptin-d8
Synonyms:1-(4-((3S,5S)-5-(thiazolidine-3-carbonyl)pyrrolidin-3-yl)piperazin-1-yl)butane-1,3-dione-d8; Teneligliptin Impurity G-d8
Molecular Formula:C₁₆H₁₈D₈N₄O₃S
Molecular Weight:362.52
Category:Building Blocks; Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N4-Des Pyrazolo N4-Acetoacetyl Teneligliptin-d8 is labelled N4-Des Pyrazolo N4-Acetoacetyl Teneligliptin (D297285) which is an impurity of Teneligliptin (T018300, Hydrobromide salt), a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion, and has a half-life of 24.2 hours in the human body.
References:Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)
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