CAS:654655-80-8|Bedaquiline (Mixture of Diastereomers)

Catalogue Number:B119550
Chemical Name:Bedaquiline (Mixture of Diastereomers)
Synonyms:6-Bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol;
CAS Number:654655-80-8
Molecular Formula:C₃₂H₃₁BrN₂O₂
Appearance:Off-White to Pale Yellow Solid
Melting Point:>164°C (dec.)
Molecular Weight:555.5
Storage:-20°C
Solubility:Acetonitrile (Slightly, Heated) Chloroform (Slightly, Heated), DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Bedaquiline is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References:de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);
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