CAS:1185240-22-5|A77 1726-d4

Catalogue Number:A771727
Chemical Name:A77 1726-d4
Synonyms:N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide-d4, LEF-M-d4; Teriflunomide-d4
CAS Number:1185240-22-5
Alternate CAS #
163451-81-8 unlabelled
Molecular Formula:C₁₂H₅D₄F₃N₂O₂
Appearance:White to Off-White Solid
Melting Point:230-232°C
Molecular Weight:274.23
Storage:-20°C
Solubility:Acetonitrile (Very Slightly), DMSO (Slightly)
Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors;
Applications:The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)
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