CAS:1253056-18-6|3-Desamino-2,3-dehydro Sitagliptin

CAS:1253056-18-6|3-Desamino-2,3-dehydro Sitagliptin

Catalogue Number:D281985
Chemical Name:3-Desamino-2,3-dehydro Sitagliptin
Synonyms:(E)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one; (2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one;
Impurity:Sitagliptin Tablets EP Impurity FP-D
CAS Number:1253056-18-6
Molecular Formula:C₁₆H₁₂F₆N₄O
Appearance:Colourless to Pale Yellow Gel to Waxy Solid
Melting Point:N/A
Molecular Weight:390.29
Storage:-20°C
Solubility:DMSO (Slightly), Methanol
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Desamino-2,3-dehydro Sitagliptin is an impurity of Sitagliptin (S491000)
References:Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005);
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