CAS:1675201-16-7|3-Desamino Acetoxy Sitagliptin

Catalogue Number:D281983
Chemical Name:3-Desamino Acetoxy Sitagliptin
Synonyms:4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl Acetate
CAS Number:1675201-16-7
Molecular Formula:C₁₈H₁₆F₆N₄O₃
Appearance:Oil to semi-solid
Molecular Weight:450.34
Solubility:Chloroform
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Desamino Acetoxy Sitagliptin is a by-product in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985) which is an impurity of Sitagliptin (S491000)
References:Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005); Bergman, A., et al: Clin. Ther. 28, 55 (2006)
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