CAS:1374356-45-2|(S)-Crizotinib

Catalogue Number:C785005
Chemical Name:(S)-Crizotinib
Synonyms:3-[(1S)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
CAS Number:1374356-45-2
Alternate CAS #
R-isomer: 877399-52-5
Molecular Formula:C₂₁H₂₂Cl₂FN₅O
Appearance:White to Light Yellow Solid
Melting Point:197 – 200°C
Molecular Weight:450.34
Storage:-20°C, Inert atmosphere
Solubility:Acetonitrile (Slightly), Chloroform (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(S)-Crizotinib is the S-isomer of Crizotinib (C785000) and a novel potent, selective, and cell permeable MTH1 inhibitor. (S)-Crizotinib can also serve as a promising anticancer agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Huber, K.V.M., et al.: Nature, 508, 222 (2014)
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