CAS:172602-83-4|1-Cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester

Catalogue Number:C988505
Chemical Name:1-Cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
CAS Number:172602-83-4
Molecular Formula:C₁₇H₁₇F₂NO₄
Appearance:White Solid
Melting Point:147-150°C
Molecular Weight:337.32
Storage:4°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-Cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester is used in the preparation of alkoxyquinolone antibacterial agents. Also an impurity in the synthesis of Moxifloxacin (M745000), a fluorinated quinolone antibacterial.
References:Sanchez, J. et al.: J. Med. Chem., 38, 4478 (1995); Woodcock, J.M., et al.: Antimicrob. Ag. Chemother., 41, 101 (1997), Stass, H., et al.: Antimicrob. Ag. Chemother., 42, 2060 (1998)
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