CAS:22518-27-0|4-(4-Chlorophenyl)-2-pyrrolidinone

Catalogue Number:C379450
Chemical Name:4-(4-Chlorophenyl)-2-pyrrolidinone
Synonyms:2-Pyrrolidinone, 4-(p-chlorophenyl)- (8CI); (±)-Baclofen Lactam; 4-(4-Chlorophenyl)-2-pyrrolidinone; 4-(4-Chlorophenyl)-2-pyrrolidone; USP Baclofen Related Compound A;
Impurity:Baclofen EP Impurity A
CAS Number:22518-27-0
Molecular Formula:C₁₀H₁₀ClNO
Appearance:White Solid
Melting Point:115-117°C
Molecular Weight:195.65
Storage:-20°C
Solubility:Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category:Research Tools; Miscellaneous;
Applications:4-(4-Chlorophenyl)-2-pyrrolidinone is used in the preparation of potential and selective antagonists of the a1A adrenergic receptor (1,2). It is an impurity of Baclofen (B108000), a specific GABA-B receptor agonist. Muscle relaxant (skeletal).
References:(1) Whitlock, G. et al.: Bioorg. med. Chem. Lett., 19, 3118 (2009)
(2) Brogden, R.N., et al.: Drugs, 8,1 (1974)
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