CAS:40443-01-4|5-(2-Chloroethylidene)-10,11-dihydro-5H-Dibenzo[a,d]cycloheptene

Catalogue Number:C368275
Chemical Name:5-(2-Chloroethylidene)-10,11-dihydro-5H-Dibenzo[a,d]cycloheptene
CAS Number:40443-01-4
Molecular Formula:C₁₇H₁₅Cl
Molecular Weight:254.75
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-(2-Chloroethylidene)-10,11-dihydro-5H-Dibenzo[a,d]cycloheptene is used as a regeant in the synthesis of [(dihydrodibenzocyclohepthylidene)ethyl]piperazine derivatives which exhibit vasodilatory activity similar to common drugs such as cinnarizine and flunarizine. It may also be used in the preparation of N-(dihydrodibenzocycloheptenylideneethyl)ephedrines which are anti-ulcer agents.
References:Cirera, X., et al.: Preparation of N-(dihydrodibenzocycloheptenylideneethyl)ephedrines as antiulcer agents, US Patent 4835179, May 30, 1989; Cirera, X., et al.: Vasodilatory [(dihydrodibenzocyclohepthylidene)ethyl]piperazine derivatives and process for the preparation of these compounds, US Patent 4835156, May 30, 1989
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