CAS:503612-76-8|4-Demethoxy-4-hydroxy Apixaban

Catalogue Number:D231405
Chemical Name:4-Demethoxy-4-hydroxy Apixaban
Synonyms:4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;
CAS Number:503612-76-8
Molecular Formula:C₂₄H₂₃N₅O₄
Appearance:White to Pale Beige Solid
Melting Point:>250°C (dec.)
Molecular Weight:445.47
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Stability
Hygroscopic
Category:Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Demethoxy-4-hydroxy Apixaban is a metabolite of Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa.
References:Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);
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