CAS:5959-18-2|N-(4-Aminobenzoyl)-D-glutamic Acid

Catalogue Number:A593820
Chemical Name:N-(4-Aminobenzoyl)-D-glutamic Acid
Synonyms:D-N-(p-Aminobenzoyl)glutamic Acid
CAS Number:5959-18-2
Molecular Formula:C₁₂H₁₄N₂O₅
Appearance:Pale Yellow Solid
Molecular Weight:266.25
Solubility:Dichloromethane, Ethyl Acetate, Methanol, Water
Category:Standards; Amino Acids;
Applications:N-(4-Aminobenzoyl)-D-glutamic acid is an intermediate in the synthesis of R-Methotrexate which is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
References:Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),
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