Des-difluoro-oxo Des-(methyl ((S)-1-((1R,3S,4S)-3-(1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptan-2-yl)-3-methyl-1-oxobutan-2-yl)carbamate) Ledipasvir

Chemical Name:Des-difluoro-oxo Des-(methyl ((S)-1-((1R,3S,4S)-3-(1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptan-2-yl)-3-methyl-1-oxobutan-2-yl)carbamate) Ledipasvir
Synonyms:Ledipasvir Keto Impurity-1
Molecular Formula:C₂₉H₂₉BrN₄O₄
Molecular Weight:577.47
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ledipasvir Keto Impurity-1 can be obtained from (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic Acid (CAS 1129634-44-1) which can be also be used as reactant or reagent in synthetic preparation for thrombin inhibitors.
References:Plummer, C. W., et al.: PCT Int. Appl., WO 2014028318 A1 20140220 (2014)
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