N-Desmethyl (Z)-Doxepin Hydrochloride

Chemical Name:N-Desmethyl (Z)-Doxepin Hydrochloride
Synonyms:(3Z)-3-Dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-1-propanamine Hydrochloride; (Z)-3-Dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-1-propanamine Hydrochloride; Dibenz[b,e]oxepin 1-Propanamine deriv.
CAS Number:124694-02-6
Alternate CAS #:Free base: 58534-46-6; E-isomer: 4504-96-5
Molecular Formula:C₁₈H₂₀ClNO
Molecular Weight:301.81
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Desmethyl (Z)-Doxepin Hydrochloride is an impurity of Doxepin Hydrochloride (D550000); a compound used clinically to treat anxiety and depression. N-Desmethyl (Z)-Doxepin Hydrochloride is also used for treatment of sleeping disorders.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Ribbentrop, A., et al.: Arzneim.-Forsch., 15, 863 (1965); Hobbs, D.C., et al.: Biochem. Pharmacol., 18, 1941 (1969); Pinder, R.M., et al.: Drugs, 13, 161 (1977); Shrivastava, R.K., et al.: Clin. Ther., 7, 181 (1985); Kavey, N.B., et al.: PCT Int. Appl. WO 2007136741 A2 20071129. Nov 29, 2007
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