Drug Delivery

Chemical Name:p-Hydroxyatazanavir-d4Synonyms:3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(p-hydroxyphenyl-d4-methyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-dimethyl EsterAlternate CAS #:Unlabelled CAS# N/AMolecular Formula:C₃₈H₄₈D₄N₆O₈Molecular Weight:724.88Category:Building Blocks; Isotopic Labeled Analogues;Applications:p-Hydroxyatazanavir-d4 is the labeled analog of p-Hydroxyatazanavir (H828175), a metabolite of Atazanavir (A790051), a novel azapeptide HIV protease inhibitor (PI). Antiviral.References:Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998); Nolan, D., et al.: Drugs, 63(23), 2555 (2003); Musial, B.L., et […]

Chemical Name:1,8,15,22,29,36-hexaazacyclodotetracontane-2,9,16,23,30,37-hexaoneCAS Number:865-14-5Molecular Formula:C36H66N6O6Molecular Weight:678.96To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature […]

Chemical Name:Hydroxy CobicistatSynonyms:Thiazol-5-ylmethyl ((2R,5R)-5-((S)-2-(3-((2-(2-Hydroxypropan-2-yl)thiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanamido)-1,6-diphenylhexan-2-yl)carbamateCAS Number:1051463-40-1Molecular Formula:C₄₀H₅₃N₇O₆S₂Molecular Weight:792.02Category:Standards; Enzyme Activators and Inhibitors;Applications:Hydroxy Cobicistat is a derivative of Cobicistat (C633150), a HIV protease inhibitor that has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer.References:Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: […]

Chemical Name:1-Hydroxy Carvedilol-d3 1-O-β-D-GlucuronideSynonyms:4-[2-Hydroxy-3-[[2-(2-methoxy-d3-phenoxy)ethyl]amino]propoxy]-9H-carbazol-1-yl β-D-Glucopyranosiduronic AcidAlternate CAS #:Unlabelled: 131087-98-4Molecular Formula:C₃₀H₃₁D₃N₂O₁₁Molecular Weight:601.62Category:Building Blocks; Isotopic Labeled Analogues;Applications:1-Hydroxy Carvedilol-d3 1-O-β-D-Glucuronide is the labeled analogue of 1-Hydroxy Carvedilol 1-O-β-D-Glucuronide (H825035), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.References:Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Fujimaki, M. & Hakusui, H.: Xenobiotica, 20, 1025 […]

Chemical Name:18-Hydroxy Corticosterone-d8Synonyms:(11β)-11,18,21-Trihydroxypregn-4-ene-3,20-dione-d8; 11β,18,21-Trihydroxypregn-4-ene-3,20-dione-d8; 18-Hydroxycorticosterone-d8;Alternate CAS #:561-65-9-unlabelledMolecular Formula:C₂₁H₂₂D₈O₅Molecular Weight:370.51Category:Building Blocks; Isotopic Labeled Analogues;Applications:Labelled 18-Hydroxycorticosterone (H824960). 18-Hydroxycorticosterone is a derivative of Corticosterone. 18-Hydroxycorticosterone is used as an intermediate in the synthesis of Aldosterone (A514700).References:Mulatero, P., et al.: J. Clin. Endocrinol. Metab., 83, 3996 (1998); Funder, J., et al.: J. Clin. Endocrinol. Metab., 93, 3266 (2008); Mulatero, […]

Chemical Name:(R)-7-Hydroxy EfavirenzSynonyms:(R)-6-Chloro-4-(cyclopropylethynyl)-7-hydroxy-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-oneMolecular Formula:C₁₄H₉ClF₃NO₃Molecular Weight:331.67Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;Applications:(R)-7-Hydroxy Efavirenz, is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.References:Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped […]

Chemical Name:4-Hydroxy-Tamoxifen Acyl-glucuronideMolecular Formula:C₃₃H₃₇NO₁₀Molecular Weight:607.65Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:4-Hydroxy-Tamoxifen Acyl-glucuronide, is an impurity of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.References:Sutherland, R., et al.: Nature, 267, 434 (1977), Lerner, L., et al.: Cancer Res., 50, 4177 (1990), Love, R., et al.: J. Clin. Oncol., 20 2559 (2002),To ensure […]

Chemical Name:4-Hydroxy-β-Carboxy Tamoxifen N-β-D-GlucuronideMolecular Formula:C₃₃H₃₇NO₁₀Molecular Weight:607.65Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:4-Hydroxy-β-Carboxy Tamoxifen N-β-D-Glucuronide, is an impurity of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.References:Sutherland, R., et al.: Nature, 267, 434 (1977), Lerner, L., et al.: Cancer Res., 50, 4177 (1990), Love, R., et al.: J. Clin. Oncol., 20 2559 […]

Chemical Name:11-Hydroxyasenapine-13CD3Synonyms:(3aR,12bR)-rel-11-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-5-ol-13CD3CAS Number:1391744-99-2Alternate CAS #:Unlabelled: 1391744-99-2Molecular Formula:C₁₆¹³CH₁₃D₃ClNO₂Molecular Weight:305.78Category:Building Blocks; Isotopic Labeled Analogues;Applications:Isotope labelled analogue of 11-Hydroxyasenapine is an metabolite of asenapine (A788000). Asenapine is an serotonin (5HT2) and dopamine (D2) receptor antagonist.References:Meltzer, H., et al.: J. Pharmacol. Exp. Ther., 251, 238 (1989); Schotte, A., et al.: Brain Res., 631, 191 (1993); Andree, B., et al.: […]

Chemical Name:6-Hydroxy Alosetron-d3Synonyms:2,3,4,5-Tetrahydro-6-hydroxy-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one-d3; 2,3,4,5-Tetrahydro-6-hydroxy-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one-d3; 6-Hydroxy Lotronex-d3Alternate CAS #:Unlabelled: 128486-89-5Molecular Formula:C₁₇H₁₅D₃N₄O₂Molecular Weight:313.37Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Isotope labelled 6-Hydroxy Alosetron is a derivative of Alosetron (A575500), serotonin 5HT3-receptor antagonist. Used in treatment of irritable bowel syndrome.References:Camilleri, M., et al.: Lancet, 355, 1035 (2000), Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002), Lewis, D., […]